Article
Advances in the pharmacological management of acute myeloid leukemia in adults.
Expert opinion on pharmacotherapy - 1 Sept 2022
Numan Yazan, Abaza Yasmin, Altman Jessica K, Platanias Leonidas C
Abstract excerpt
INTRODUCTION: With advances in molecular medicine and precision approaches, there has been significant improvement in the treatment of acute myeloid leukemia (AML) in recent years. This reflects better understanding of molecular and metabolic pathways in leukemia cells, including BCL2 upregulation that prevents apoptosis, FLT3 tyrosine kinase activating mutations that allow uncontrolled proliferation, and IDH...
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