Article
Association between interferon lambda 3 rs12979860 polymorphism and clinical outcome in dengue virus-infected children.
International journal of immunogenetics - 1 Aug 2020
da Silva Cezar Renata Duarte, da Silva Castanha Priscila Mayrelle, Matos Freire Naishe, Mola Carla, Feliciano do Carmo Rodrigo, Tenório Cordeiro Marli, Baptista Paulo, Silva Vasconcelos Luydson Richardson, Moura Patrícia, da Silva Teixeira Vanessa Gabryelle
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in immune-related genes have been shown to play a role in driving the development of the severe phenotypes of dengue virus (DENV) infection. We assessed the association between IFNL3 gene SNP (rs12979860) and dengue clinical outcomes in children. Patients with dengue-related symptoms (aged 1-15 years) admitted at a public hospital in Northeast Brazil were invited to...
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