Article
Pre-transplant Quantitative Determination of NPM1 Mutation Significantly Predicts Outcome of AIlogeneic Hematopoietic Stem Cell Transplantation in Patients with Normal Karyotype AML in Complete Remission.
Anticancer research - 1 Oct 2016
Karas Michal, Steinerova Katerina, Lysak Daniel, Hrabetova Marcela, Jungova Alexandra, Sramek Jiri, Jindra Pavel, Polivka Jiri, Holubec Lubos
Abstract excerpt
BACKGROUND/AIM: Minimal residual disease (MRD) in patients with acute myeloid leukemia (AML) before allogeneic hematopoietic stem cell transplantation (alloHSCT) can influence the results of therapy. With the aim of evaluating the potential role of pre-transplant MRD, we studied the impact of pre-transplant MRD level on the outcome of alloHSCT in patients with AML in complete remission (CR). PATIENTS AND METHODS:...
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