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Association of PFN1 Gene Polymorphisms with Bone Mineral Density, Bone Turnover Markers, and Osteoporotic Fractures in Chinese Population.

Calcified tissue international - 1 Aug 2023

Wu Yinghao, Wu Shengting, Yang Erzhu, Zhang Guowang, Shi Qiang, Liang Jiaming, Lian XiaoFeng, Xu JianGuang

Abstract excerpt

Recent studies have discovered an association between the PFN1 gene and Paget's disease. However, it is currently unknown whether the PFN1 gene is related to osteoporosis. This study was performed to investigate the association of Single-Nucleotide Polymorphisms (SNPs) in the PFN1 gene with Bone Mineral Density (BMD) as well as bone turnover markers and osteoporotic fractures in Chinese subjects. A total of 2836...

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PMID: 37401976
DOI: 10.1007/s00223-023-01102-2

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