Article
A haplotype of MATN3 is associated with vertebral fracture in Chinese postmenopausal women: Peking Vertebral Fracture (PK-VF) study.
Bone - 1 Apr 2012
Zhao Jing, Xia Weibo, Nie Min, Zheng Xin, Wang Qiuping, Wang Xiran, Wang Wenbo, Ning Zhiwei, Huang Wei, Jiang Yan, Li Mei, Wang Ou, Xing Xiaoping, Sun Yue, Luo Lianmei, He Shuli, Yu Wei, Lin Qiang, Pei Yu, Zhang Fan, Han Youxia, Tong Yanmin, Che Ying, Shen Ruixin, Hu Yingying, Zhou Xueying, Chen Qian, Xu Ling
Abstract excerpt
The Matrilin3 gene (MATN3) encodes an extracellular matrix protein, which modulates chondrocyte differentiation. The aim of this study was to test for association of MATN3 polymorphisms with bone mineral density (BMD), fracture, vertebral fracture, bone turnover or 25-hydroxyvitamin D [25(OH)D] in postmenopausal women. A community-based population of 1488 postmenopausal women was randomly selected in Beijing. The...
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