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Article

Common Variants in OPG Confer Risk to Bone Mineral Density Variation and Osteoporosis Fractures.

Scientific reports - 11 May 2017

Sheng Xiaoyong, Cai Guangyong, Gong Xingjun, Yao Zouying, Zhu Ye

Abstract excerpt

Although many common variants have been identified for bone mineral density (BMD) and osteoporosis fractures, all the identified risk variants could only explain a small portion of heritability of BMD and osteoporosis fractures. OPG belongs to the tumor necrosis factor receptor superfamily, which plays a crucial role in bone remodeling and is thus a promising candidate gene of osteoporosis. Several studies have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28496203
DOI: 10.1038/s41598-017-01579-6
PMCID: PMC5432005

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