Article
Association of PLXNA2 polymorphisms with vertebral fracture risk and bone mineral density in postmenopausal Korean population.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jan 2006
Hwang J-Y, Lee J-Y, Park M-H, Kim K-S, Kim K-K, Ryu H-J, Lee J-K, Han B G, Kim J W, Oh B, Kimm K, Park B L, Shin H D, Kim T-H, Hong J M, Park E K, Kim D J, Koh J-M, Kim G S, Kim S-Y
Abstract excerpt
INTRODUCTION: Plexin A2 (PLXNA2) is a receptor that recognizes secreted or membrane-bound semaphorin 3A, which is implicated in neural regulation of bone metabolism. MATERIALS AND METHODS: In the present study, we identified 48 genetic polymorphisms in PLXNA2 by resequencing, and 10 single nucleotide polymorphisms (SNPs) were selected for further investigation into their potential involvement in osteoporosis in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.