Article
Expression profiling of primary and metastatic ovarian tumors reveals differences indicative of aggressive disease.
PloS one - 1 Jan 2014
Brodsky Alexander S, Fischer Andrew, Miller Daniel H, Vang Souriya, MacLaughlan Shannon, Wu Hsin-Ta, Yu Jovian, Steinhoff Margaret, Collins Colin, Smith Peter J S, Raphael Benjamin J, Brard Laurent
Abstract excerpt
The behavior and genetics of serous epithelial ovarian cancer (EOC) metastasis, the form of the disease lethal to patients, is poorly understood. The unique properties of metastases are critical to understand to improve treatments of the disease that remains in patients after debulking surgery. We sought to identify the genetic and phenotypic landscape of metastatic progression of EOC to understand how metastases...
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