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Article

Association of TIM-3 with anterior uveitis and associated systemic immune diseases: a Mendelian randomization analysis

15 Jun 2023

Abstract excerpt

Background We aimed to investigate the causal association between TIM-3, an immune checkpoint inhibitor, and anterior uveitis (AU), as well as associated systemic immune diseases. Materials and methods We performed two-sample Mendelian randomization (MR) analyses to estimate the causal effects of TIM-3 on AU and three associated systemic diseases, namely ankylosing spondylitis (AS), Crohn's disease (CD), and...

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PMID: 37396905
DOI: 10.3389/fmed.2023.1183326

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