Article
Integrative single-cell transcriptomics and mendelian randomization identifies BTN3A2 as a shared protective factor in Behçet's disease and inflammatory bowel disease.
Frontiers in immunology - 1 Jan 2026
Dai Qinjin, Wu Yuelan, Geng Wenbo, Li Mengna, Zhang Wanyun, Lai Yuxian, Zhang Pei, Zhou Chunjiang, Wang Yinuo, Cao Qingfeng, Luo Xiang, Lai Yujie, Huang Changwei, Yang Peizeng
Abstract excerpt
Background: Behçet's disease (BD) and inflammatory bowel disease (IBD) are immune-mediated chronic inflammatory disorders. Although they exhibit significant overlap in clinical manifestations and immunological features, whether they share molecular targets and pathogenic links remains unclear. This study aimed to explore the possible linking and shared treatment target between these two diseases. Methods: We...
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