Article
Comparative analysis of genomic profiles between tissue-based and plasma-based next-generation sequencing in patients with non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Aug 2023
Lin Zeyun, Li Yuqin, Tang Shiqi, Deng Qiuhua, Jiang Juhong, Zhou Chengzhi
Abstract excerpt
OBJECTIVES: Genotype-guided personalized therapy has become an essential part of routine clinical care in non-small cell lung cancer (NSCLC) patients. However, small tissue specimens often yield inadequate molecular testing material. Plasma ctDNA-based liquid biopsy is an increasingly common non-invasive alternative to tissue biopsy. This study examined the similarities and differences in the molecular profiling...
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