Article
High concordance of actionable genomic alterations identified between circulating tumor DNA-based and tissue-based next-generation sequencing testing in advanced non-small cell lung cancer: The Korean Lung Liquid Versus Invasive Biopsy Program.
Cancer - 15 Aug 2021
Park Sehhoon, Olsen Steve, Ku Bo Mi, Lee Min-Sang, Jung Hyun-Ae, Sun Jong-Mu, Lee Se-Hoon, Ahn Jin Seok, Park Keunchil, Choi Yoon-La, Ahn Myung-Ju
Abstract excerpt
BACKGROUND: Because of the growing number of actionable biomarkers in non-small cell lung cancer (NSCLC), sufficient tissue availability for testing is becoming a greater challenge. Liquid biopsy offers a potential solution by complementing standard tissue-based methods. In this study, the authors analyzed the concordance of actionable genomic alterations sequenced from circulating tumor DNA (ctDNA; Guardant360)...
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