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Article

Concordance of Genomic Alterations by Next-Generation Sequencing in Tumor Tissue versus Cell-Free DNA in Stage I-IV Non-Small Cell Lung Cancer.

The Journal of molecular diagnostics : JMD - 1 Feb 2020

Jiang John, Adams Hans-Peter, Yao Lijing, Yaung Stephanie, Lal Preeti, Balasubramanyam Aarthi, Fuhlbrück Frederike, Tikoo Nalin, Lovejoy Alexander F, Froehler Sebastian, Fang Li Tai, Achenbach H Jost, Floegel Ralph, Krügel Rainer, Palma John F

Abstract excerpt

Molecular biomarkers hold promise for personalization of cancer treatment. However, a typical tumor biopsy may be difficult to acquire and may not capture genetic variations within or across tumors. Given these limitations, tumor genotyping using next-generation sequencing of plasma-derived circulating tumor (ct)-DNA has the potential to transform non-small cell lung cancer (NSCLC) management. Importantly,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31837429
DOI: 10.1016/j.jmoldx.2019.10.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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