Article
Maternal glycemia in pregnancy is longitudinally associated with blood DNAm variation at the FSD1L gene from birth to 5 years of age.
Clinical epigenetics - 29 Jun 2023
Taschereau Amélie, Thibeault Kathrine, Allard Catherine, Juvinao-Quintero Diana, Perron Patrice, Lutz Sharon M, Bouchard Luigi, Hivert Marie-France
Abstract excerpt
BACKGROUND: In utero exposure to maternal hyperglycemia has been associated with an increased risk for the development of chronic diseases in later life. These predispositions may be programmed by fetal DNA methylation (DNAm) changes that persist postnatally. However, although some studies have associated fetal exposure to gestational hyperglycemia with DNAm variations at birth, and metabolic phenotypes in...
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