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Article

DNA methylation profiles in sibling pairs discordant for intrauterine exposure to maternal gestational diabetes.

Epigenetics - 1 Jan 2017

Kim Eunae, Kwak Soo Heon, Chung Hye Rim, Ohn Jung Hun, Bae Jae Hyun, Choi Sung Hee, Park Kyong Soo, Hong Joon-Seok, Sung Joohon, Jang Hak Chul

Abstract excerpt

Intrauterine exposure to hyperglycemia is reported to confer increased metabolic risk in later life, supporting the 'developmental origins of health and disease' hypothesis. Epigenetic alterations are suggested as one of the possible underlying mechanisms. In this study, we compared pairwise DNA methylation differences between siblings whose intrauterine exposure to maternal gestational diabetes (GDM) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29099273
DOI: 10.1080/15592294.2017.1370172
PMCID: PMC5788413

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