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Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring.

Human molecular genetics - 1 Jun 2015

Finer Sarah, Mathews Chris, Lowe Rob, Smart Melissa, Hillman Sara, Foo Lin, Sinha Ajay, Williams David, Rakyan Vardhman K, Hitman Graham A

Abstract excerpt

Exposure of a developing foetus to maternal gestational diabetes (GDM) has been shown to programme future risk of diabetes and obesity. Epigenetic variation in foetal tissue may have a mechanistic role in metabolic disease programming through interaction of the pregnancy environment with gene function. We aimed to identify genome-wide DNA methylation variation in cord blood and placenta from offspring born to...

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PMID: 25634562
DOI: 10.1093/hmg/ddv013

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MVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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