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Article

Rapid development of cefiderocol resistance in a carbapenem-resistant Pseudomonas aeruginosa isolate associated with mutations in the pyoverdine biosynthesis pathway.

Journal of global antimicrobial resistance - 1 Sept 2023

Brakert Luise, Berneking Laura, Both Anna, Berinson Benjamin, Huang Jiabin, Aepfelbacher Martin, Wolschke Christine, Wichmann Dominic, Rohde Holger

Abstract excerpt

Here we report the in vivo development of cefiderocol resistance within 11 days after therapy initiation in a critically ill patient with bloodstream infection, infection of peri-anal fistula, and pneumonia caused by a VIM-2 harbouring, carbapenem-resistant Pseudomonas aeruginosa. Compared to a cefiderocol-naïve P. aeruginosa blood culture isolate, agar diffusion susceptibility testing found a reduced cefiderocol...

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Identifiers

PMID: 37379881
DOI: 10.1016/j.jgar.2023.06.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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