The Association of DNA Ligase 1 Rs20579 Polymorphism With Lung Cancer Risk Among Taiwanese.

doi:10.21873/invivo.13235

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The Association of DNA Ligase 1 Rs20579 Polymorphism With Lung Cancer Risk Among Taiwanese.

In vivo (Athens, Greece) - 1 Jan 2000

Chang Shang-Miao, Yang Ya-Chen, Chen Guan-Liang, Chen Li-Hsiou, Shen Te-Chun, Liu Yen-Feng, Wang Yun-Chi, Tsai Chia-Wen, Hsia Te-Chun, Bau DA-Tian, Chang Wen-Shin

Abstract excerpt

BACKGROUND/AIM: Impaired DNA repair capacity may play a critical role in genome instability and carcinogenesis. However, the impact of DNA ligase 1 (Lig1) genotypes on tumorigenesis remains unclear. This study aimed to investigate the contribution of Lig1 rs20579 genotypes to the risk of developing lung cancer, and review the related literature. MATERIALS AND METHODS: Polymerase chain reaction-restriction...

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Identifiers

PMID: 37369482
DOI: 10.21873/invivo.13235
PMCID: PMC10347960

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