Revealing the Association of LIG1 Genetic Variants With Pterygium Susceptibility and Demographic Characteristics in a Taiwanese Population.

doi:10.21873/invivo.14422

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Revealing the Association of LIG1 Genetic Variants With Pterygium Susceptibility and Demographic Characteristics in a Taiwanese Population.

In vivo (Athens, Greece) - 1 Jan 2026

Hu Pei-Shin, Hsia Ning-Yi, Mong Mei-Chin, Hsia Te-Chun, Chen Jaw-Chyun, Tsai Chia-Wen, Bau DA-Tian, Chang Wen-Shin

Abstract excerpt

BACKGROUND/AIM: Pterygium is a common ocular surface disorder associated with long-term ultraviolet exposure and/or oxidative DNA damage. Accumulated evidence suggests that defects in DNA repair pathways may contribute to pterygium risk. DNA ligase I (LIG1), a key enzyme involved in DNA replication and base excision repair, has been involved in the etiology of several human diseases, including cancers. However,...

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PMID: 42665426
DOI: 10.21873/invivo.14422
PMCID: PMC13531138

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LIG1

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