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Article

FSP1: a key regulator of ferroptosis

24 Jun 2023

Abstract excerpt

Ferroptosis suppressor protein 1 (FSP1) is one of the main regulatory molecules of ferroptosis. FSP1 functions through the FSP1-coenzyme Q10 (CoQ10)-NAD(P)H axis and the vitamin K redox cycle. FSP1 is regulated by upstream factors, including transcription factors and noncoding RNA (ncRNA), and is subject to epigenetic modifications, which affect the progress of FSP1-related diseases. FSP1 is closely associated...

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Ferroptosis and cancer prognosis
RNA modifications and cancer
Cancer, Lipids, and Metabolism

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37357101
DOI: 10.1016/j.molmed.2023.05.013

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