Effects of naturally occurring S47F/A mutations on the structure and function of human cytochrome c.

doi:10.1016/j.jinorgbio.2023.112296

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Article

Effects of naturally occurring S47F/A mutations on the structure and function of human cytochrome c.

Journal of inorganic biochemistry - 1 Sept 2023

Li Yan-Yan, Long Shuang-Shuang, Yu Lu, Liu Ao-Kun, Gao Shu-Qin, Tan Xiangshi, Lin Ying-Wu

Abstract excerpt

The sequence and structure of human cytochrome c (hCyt c) exhibit evolutionary conservations, with only a limited number of naturally occurring mutations in humans. Herein, we investigated the effects of the naturally occurring S47F/A mutations on the structure and function of hCyt c in the oxidized form. Although the naturally occurring S47F/A mutations did not largely alter the protein structure, the S47F and...

Topics

Humans
Cytochromes c
Kinetics
Hydrogen Peroxide
Mutation

Source

Open in PubMed

Identifiers

PMID: 37356378
DOI: 10.1016/j.jinorgbio.2023.112296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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