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Article

Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c.

Archives of biochemistry and biophysics - 1 Nov 2017

Khan Sabab Hasan, Islam Asimul, Hassan Md Imtaiyaz, Sharma Sujata, Singh Tej Pal, Ahmad Faizan

Abstract excerpt

A sequence alignment of horse cytochrome c (cyt c) with all known cyts c shows that Leu at position 94 is conserved, except in 14 species which have either Val or Ile at this position. It is also known that Leu94 of the mammalian cyt c plays an important role in folding and stability. The important question here is as to what will happen in terms of folding and stability if Leu94 of the mammalian cyt c is...

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Identifiers

PMID: 28851624
DOI: 10.1016/j.abb.2017.08.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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