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Article

Effect of nitration on the physicochemical and kinetic features of wild-type and monotyrosine mutants of human respiratory cytochrome c.

Biochemistry - 25 Nov 2008

Rodríguez-Roldán Vicente, García-Heredia José Manuel, Navarro José A, De la Rosa Miguel A, Hervás Manuel

Abstract excerpt

The effect of tyrosine nitration on the physicochemical properties and reactivity of human respiratory cytochrome c has been extensively analyzed. A set of mutants, each bearing only one tyrosine out of the five present in the wild-type molecule, has been constructed in order to study the effect of each tyrosine nitration on the properties of the whole protein. Replacement of tyrosines by phenylalanines does not...

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PMID: 18956889
DOI: 10.1021/bi800910v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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