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Article

The impacts of the mitochondrial myopathy-associated G58R mutation on the dynamic structural properties of CHCHD10.

Journal of biomolecular structure & dynamics - 1 Jul 2024

Alici Hakan, Uversky Vladimir N, Kang David E, Woo Junga Alexa, Coskuner-Weber Orkid

Abstract excerpt

The mitochondria are responsible for producing energy within the cell, and in mitochondrial myopathy, there is a defect in the energy production process. The CHCHD10 gene codes for a protein called coiled-coil-helix-coiled-coil-helix domain-containing protein 10 (CHCHD10), which is found in the mitochondria and is involved in the regulation of mitochondrial function. G58R mutation has been shown to disrupt the...

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Identifiers

PMID: 37349880
DOI: 10.1080/07391102.2023.2227713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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