Article
Primary membranous nephropathy in two siblings with one combined with anti-glomerular basement membrane disease: a case report.
BMC nephrology - 22 Jun 2023
Cheng Yan-Jiao, Jia Xiao-Yu, Cao Hong-Ru, Zhao Xiao-Yi, Zhou Xu-Jie, Yu Xiao-Juan, Xu Rong, Zhou Fu-de, Wang Su-Xia, Cui Zhao, Zhao Ming-Hui
Abstract excerpt
BACKGROUND: The phospholipase A2 receptor (PLA2R) associated with membranous nephropathy (MN) is an organ-specific autoimmune disease associated with PLA2R and human leukocyte antigen (HLA) genes. Familial PLA2R-related MN is rarely reported. The combination of anti-GBM disease and MN has been well documented, though the mechanism behind it remains unclear. CASE PRESENTATION: We describe two siblings diagnosed...
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