Article
Dynamics of single-base editing: Theoretical analysis.
The Journal of chemical physics - 28 Jun 2023
Vardanyan Vardan Hoviki, Wang Qian, Kolomeisky Anatoly B
Abstract excerpt
Recent experimental advances led to the development of DNA base editors (BEs) with single-nucleotide precision, which is critical for future progress in various scientific and technological fields. The molecular mechanisms of single-base discrimination, however, remain poorly understood. Using a recently developed stochastic approach, we theoretically investigated the dynamics of single-base editing. More...
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