Article
Genetic analysis of transcription factors in dopaminergic neuronal development in Parkinson's disease.
Chinese medical journal - 20 Feb 2024
Zhao Yuwen, Qin Lixia, Pan Hongxu, Song Tingwei, Wang Yige, Zhou Xiaoxia, Xiang Yaqin, Li Jinchen, Liu Zhenhua, Sun Qiying, Guo Jifeng, Yan Xinxiang, Tang Beisha, Xu Qian
Abstract excerpt
BACKGROUND: Genetic variants of dopaminergic transcription factor-encoding genes are suggested to be Parkinson's disease (PD) risk factors; however, no comprehensive analyses of these genes in patients with PD have been undertaken. Therefore, we aimed to genetically analyze 16 dopaminergic transcription factor genes in Chinese patients with PD. METHODS: Whole-exome sequencing (WES) was performed using a Chinese...
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