Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Analysis of FBXO2, FBXO6, FBXO12, and FBXO41 Variants in Han Chinese Patients with Sporadic Parkinson's Disease.

Neuroscience bulletin - 1 Oct 2017

Yuan Lamei, Song Zhi, Deng Xiong, Yang Zhijian, Yang Yan, Guo Yi, Lu Hongwei, Deng Hao

Abstract excerpt

Parkinson's disease (PD) is the second most common neurodegenerative disorder and has an elusive etiology. It is likely multifactorial, and genetic defects contribute to its pathogenesis. At least 25 genetic loci and 20 monogenic genes have been identified in monogenic PD. Recessive F-box protein 7 gene (FBXO7) mutations reportedly cause hereditary parkinsonism. To explore the roles of four paralogs (FBXO2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Ethnicity

Share to F-Box Proteins

Share to Genetic Association Studies

Share to Parkinson Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 28341977
DOI: 10.1007/s12264-017-0122-5
PMCID: PMC5636729

Genes

FBXO2
FBXO41
FBXO6
FBXO7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Analysis of FBXO2, FBXO6, FBXO12, and FBXO41 Variants in Han Chinese Patients with Sporadic Parkinson's Disease.PMID 28341977Read ↗

Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.Semantic proximity Read ↗

The role of genetics in Parkinson's disease: a large cohort study in Chinese mainland population.Semantic proximity Read ↗

Genetic analysis of the FBXO48 gene in Chinese Han patients with Parkinson disease.Semantic proximity Read ↗

Systematic mutational analysis of FBXO7 in a Parkinson's disease population from southern Spain.Semantic proximity Read ↗

A novel FBXO7-R345P mutation in a Chinese family with autosomal recessive parkinsonian-pyramidal syndrome.Semantic proximity Read ↗

F-box only protein 7 gene in parkinsonian-pyramidal disease.Semantic proximity Read ↗

The genetic spectrum of a cohort of patients clinically diagnosed as Parkinson’s disease in mainland ChinaSemantic proximity Read ↗

Novel bi-allelic FBXO7 variants in a family with early-onset typical Parkinson's diseaseSemantic proximity Read ↗

Pathophysiological mechanisms linking F-box only protein 7 (FBXO7) and Parkinson’s disease (PD)Semantic proximity Read ↗

Association between PARK16 gene polymorphisms and susceptibility of Parkinson's disease in a Chinese population.Semantic proximity Read ↗

Young-Onset Parkinson’s Disease with Impulse Control Disorder Due to Novel Variants of F-Box Only Protein 7Semantic proximity Read ↗

A genetic analysis of Chinese patients with early-onset Parkinson' s disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.