Article
Association between PIK3CA activating mutations and outcomes in early-stage invasive lobular breast carcinoma treated with adjuvant systemic therapy.
Radiology and oncology - 1 Jun 2023
Ribnikar Domen, Horvat Valentina Jeric, Ratosa Ivica, Veitch Zachary W, Grcar Kuzmanov Biljana, Novakovic Srdjan, Langerholc Erik, Amir Eitan, Seruga Bostjan
Abstract excerpt
BACKGROUND: The aim of the study was to evaluate the independent prognostic role of PIK3CA activating mutations and an association between PIK3CA activating mutations and efficacy of adjuvant endocrine therapy (ET) in patients with operable invasive lobular carcinoma (ILC). PATIENTS AND METHODS: A single institution study of patients with early-stage ILC treated between 2003 and 2008 was performed....
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