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Article

Sex-specific effects of Cre expression in Syn1Cre mice.

Scientific reports - 20 Jun 2023

Baghdadi Maarouf, Mesaros Andrea, Purrio Martin, Partridge Linda

Abstract excerpt

The Cre-loxP system has been used to generate cell-type specific mutations in mice, allowing researchers to investigate the underlying biological mechanisms of disease. However, the Cre-recombinase alone can induce phenotypes that confound comparisons among genotypes if the appropriate Cre control is not included. In this study, we characterised behavioural, morphological and metabolic phenotypes of the...

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PMID: 37340054
DOI: 10.1038/s41598-023-37029-9
PMCID: PMC10281999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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