Article
Opposing impacts of HLA-G haplotypes PROMO-G010104-UTR-3 and PROMO-G010101b/c-UTR-4 on risk of recurrent implantation failure.
Reproductive biomedicine online - 1 Sept 2023
Papúchová Henrieta, Saxtorph Malene Hviid, Hallager Trine, Jepsen Ida E, Eriksen Jens O, Persson Gry, Funck Tina, Weisdorf Iben, Macklon Nicholas, Larsen Lise Grupe, Hviid Thomas Vauvert F
Abstract excerpt
RESEARCH QUESTION: The human leukocyte antigen (HLA) class Ib molecules HLA-F and HLA-G are implicated in pregnancy success, but how do HLA-G and HLA-F genetic polymorphisms impact recurrent implantation failure (RIF)? DESIGN: Prospective cohort study at a fertility clinic including a cohort of 84 women experiencing RIF and 35 IVF controls to assess the influence of HLA-G haplotypes and diplotypes and HLA-F...
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