Article
Variation in the HLA-F gene locus with functional impact is associated with pregnancy success and time-to-pregnancy after fertility treatment.
Human reproduction (Oxford, England) - 27 Mar 2020
Langkilde Cæcilie H, Nilsson Line Lynge, Jørgensen Nanna, Funck Tina, Perin Trine L, Hornstrup Micha B, Høst Thomas, Scheike Thomas, Lindhard Anette, Hviid Thomas Vauvert F
Abstract excerpt
STUDY QUESTION: The aim of this study was to investigate a possible influence of three single nucleotide polymorphisms (SNPs) in the HLA-F gene locus on time-to-pregnancy and pregnancy success after fertility treatment. SUMMARY ANSWER: HLA-F SNP genotypes and HLA-F diplotypes are associated with the number of fertility treatment cycles needed to achieve pregnancy and live birth. WHAT IS KNOWN ALREADY: HLA class...
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