Article
Endometrial HLA-F expression is influenced by genotypes and correlates differently with immune cell infiltration in IVF and recurrent implantation failure patients.
Human reproduction (Oxford, England) - 30 Jul 2022
Papúchová Henrieta, Saxtorph Malene Hviid, Hallager Trine, Jepsen Ida E, Eriksen Jens O, Persson Gry, Funck Tina, Weisdorf Iben, Macklon Nicholas S, Larsen Lise Grupe, Hviid Thomas Vauvert F
Abstract excerpt
STUDY QUESTION: Is human leukocyte antigen (HLA)-F protein expressed in mid-secretory endometrium, and are its expression levels influenced by HLA-F gene polymorphisms and correlated with the abundance of uterine natural killer (uNK) cells and anti-inflammatory M2 macrophages? SUMMARY ANSWER: HLA-F protein is expressed in mid-secretory endometrium, and levels are correlated with immune cell infiltration, plasma...
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