Article
HLA-G regulatory haplotypes and implantation outcome in couples who underwent assisted reproduction treatment.
Human immunology - 1 Sept 2012
Costa Cynthia Hernandes, Gelmini Georgia Fernanda, Wowk Pryscilla Fanini, Mattar Sibelle Botogosque, Vargas Rafael Gustavo, Roxo Valéria Maria Munhoz Sperandio, Schuffner Alessandro, Bicalho Maria da Graça
Abstract excerpt
The role of HLA-G in several clinical conditions related to reproduction has been investigated. Important polymorphisms have been found within the 5'URR and 3'UTR regions of the HLA-G promoter. The aim of the present study was to investigate 16 SNPs in the 5'URR and 14-bp insertion/deletion (ins/del) polymorphism located in the 3'UTR region of the HLA-G gene and its possible association with the implantation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
