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Article

Phosphoregulation of DNA repair via the Rad51 auxiliary factor Swi5-Sfr1.

The Journal of biological chemistry - 1 Aug 2023

Liang Pengtao, Lister Katie, Yates Luke, Argunhan Bilge, Zhang Xiaodong

Abstract excerpt

Homologous recombination (HR) is a major pathway for the repair of DNA double-strand breaks, the most severe form of DNA damage. The Rad51 protein is central to HR, but multiple auxiliary factors regulate its activity. The heterodimeric Swi5-Sfr1 complex is one such factor. It was previously shown that two sites within the intrinsically disordered domain of Sfr1 are critical for the interaction with Rad51. Here,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37330173
DOI: 10.1016/j.jbc.2023.104929
PMCID: PMC10366545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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