Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of the Role of MAP4K4 in Focal Adhesion Dynamics and Regulation of Cell Migration of Breast Cancer Cell Line MDA-MB-231.

Archives of Razi Institute - 1 Feb 2023

Al-Fahad D, Al-Bedhawi M, Ateya H

Abstract excerpt

In the migration and metastasis of cancer cells, it is necessary to rotate the focal adhesion (FA). MAP4K4 plays a vital role in the formation of cytoskeletal regeneration, but its role in regulating FA dynamics and cancer cell migration is not well understood. This present aimed to investigate the role of MAP4K4 in regulating FA dynamics and cell migration in the human breast cancer cell line. For this purpose,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Focal Adhesions
Share to Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MCF-7 Cells

Share to Mutation

Share to Neoplasms

Share to Protein Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 37312710
DOI: 10.22092/ARI.2022.358953.2340
PMCID: PMC10258272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of the Role of MAP4K4 in Focal Adhesion Dynamics and Regulation of Cell Migration of Breast Cancer Cell Line MDA-MB-231.PMID 37312710Read ↗

Understanding the Roles of FAK in CancerSemantic proximity Read ↗

Focal adhesion dynamics in cellular function and diseaseSemantic proximity Read ↗

Tyrosine phosphorylation of paxillin alpha is involved in temporospatial regulation of paxillin-containing focal adhesion formation and F-actin organization in motile cells.Semantic proximity Read ↗

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development and TherapySemantic proximity Read ↗

Focal adhesion kinase and cancer.Semantic proximity Read ↗

New Insights on the Nuclear Functions and Targeting of FAK in CancerSemantic proximity Read ↗

Predicting how cells spread and migrateSemantic proximity Read ↗

Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer DevelopmentSemantic proximity Read ↗

Control of motile and invasive cell phenotypes by focal adhesion kinase.Semantic proximity Read ↗

Molecular aspects of tumor cell migration and invasion.Semantic proximity Read ↗

Abundant Focal Adhesion Kinase Causes Aberrant Neuronal Migration Via Its Phosphorylation at Tyr925.Semantic proximity Read ↗

Roles of focal adhesion proteins in skeleton and diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.