Article
Population size in QTL detection using quantile regression in genome-wide association studies.
Scientific reports - 13 Jun 2023
Oliveira Gabriela França, Nascimento Ana Carolina Campana, Azevedo Camila Ferreira, de Oliveira Celeri Maurício, Barroso Laís Mayara Azevedo, de Castro Sant'Anna Isabela, Viana José Marcelo Soriano, de Resende Marcos Deon Vilela, Nascimento Moysés
Abstract excerpt
The aim of this study was to evaluate the performance of Quantile Regression (QR) in Genome-Wide Association Studies (GWAS) regarding the ability to detect QTLs (Quantitative Trait Locus) associated with phenotypic traits of interest, considering different population sizes. For this, simulated data was used, with traits of different levels of heritability (0.30 and 0.50), and controlled by 3 and 100 QTLs....
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