Article
Assessing the value of phenotypic information from non-genotyped animals for QTL mapping of complex traits in real and simulated populations.
BMC genetics - 21 Jun 2016
Melo Thaise P, Takada Luciana, Baldi Fernando, Oliveira Henrique N, Dias Marina M, Neves Haroldo H R, Schenkel Flavio S, Albuquerque Lucia G, Carvalheiro Roberto
Abstract excerpt
BACKGROUND: QTL mapping through genome-wide association studies (GWAS) is challenging, especially in the case of low heritability complex traits and when few animals possess genotypic and phenotypic information. When most of the phenotypic information is from non-genotyped animals, GWAS can be performed using the weighted single-step GBLUP (WssGBLUP) method, which permits to combine all available information,...
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