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Article

Targeting HDACs in Pancreatic Neuroendocrine Tumor Models

6 Jun 2021

Abstract excerpt

Compared to pancreatic adenocarcinoma (PDAC), pancreatic neuroendocrine tumors (PanNET) represent a rare and heterogeneous tumor entity. In addition to surgical resection, several therapeutic approaches, including biotherapy, targeted therapy or chemotherapy are applicable. However, primary or secondary resistance to current therapies is still challenging. Recent genome-wide sequencing efforts in PanNET...

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PMID: 34204116
DOI: 10.3390/cells10061408

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