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Mechanisms of HDACs in cancer development

7 Apr 2025

Abstract excerpt

Histone deacetylases (HDACs) are a class of epigenetic regulators that play pivotal roles in key biological processes such as cell proliferation, differentiation, metabolism, and immune regulation. Based on this, HDAC inhibitors (HDACis), as novel epigenetic-targeted therapeutic agents, have demonstrated significant antitumor potential by inducing cell cycle arrest, activating apoptosis, and modulating the immune...

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Histone Deacetylase Inhibitors Research
Peptidase Inhibition and Analysis
Protein Degradation and Inhibitors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40260239
DOI: 10.3389/fimmu.2025.1529239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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