Article
Dynamics of the IL-33/ST2 network in the progression of human colorectal adenoma to sporadic colorectal cancer.
Cancer immunology, immunotherapy : CII - 1 Feb 2015
Cui Guanglin, Qi Haili, Gundersen Mona D, Yang Hang, Christiansen Ingrid, Sørbye Sveinung W, Goll Rasmus, Florholmen Jon
Abstract excerpt
Most sporadic colorectal cancers (CRCs) develop from preformed adenomas. Cytokines are involved in the transition from adenoma to CRC. Interleukin-33 (IL-33) is a newly discovered proinflammatory cytokine belonging to the IL-1 cytokine family and involved in the development of chronic inflammation and cancer. The aim of this study was to evaluate the dynamics of the IL-33/ST2 axis during the sequence of...
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