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Arginase 1 and L‐arginine coordinate fetal lung development and the initiation of labor in mice

9 Jun 2023

Abstract excerpt

Fetal development and parturition are precisely regulated processes that involve continuous crosstalk between the mother and the fetus. Our previous discovery that wild-type mice carrying steroid receptor coactivator (Src)-1 and Src-2 double-deficient fetuses exhibit impaired lung development and delayed labor, which indicates that the signals for parturition emanate from the fetus. In this study, we perform RNA...

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PMID: 37291976
DOI: 10.15252/embr.202256352

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