Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in Macrophages

1 Jan 2018

Abstract excerpt

Abstract Activated mouse macrophages metabolize arginine via NO synthase (NOS2) to produce NO as an antimicrobial effector. Published gene expression datasets provide little support for the activation of this pathway in human macrophages. Generation of NO requires the coordinated regulation of multiple genes. We have generated RNA-sequencing data from bone marrow–derived macrophages from representative rodent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nitric Oxide and Endothelin Effects
Share to Polyamine Metabolism and Applications
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30467554
DOI: 10.4049/immunohorizons.1700073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in MacrophagesPMID 30467554Read ↗

Arginine metabolic control of airway inflammation.Semantic proximity Read ↗

Nitric oxide in cellular adaptation and diseaseSemantic proximity Read ↗

Transcriptomic Profiles of Monocyte-Derived Macrophages in Response to Escherichia coli is Associated with the Host Genetics.Semantic proximity Read ↗

Inducible nitric oxide synthase (iNOS) regulatory region variation in non-human primates.Semantic proximity Read ↗

Arginase 1 and L‐arginine coordinate fetal lung development and the initiation of labor in miceSemantic proximity Read ↗

Arginine and Polyamines Fate in Leishmania InfectionSemantic proximity Read ↗

Response to Oxidative Burst-Induced Hypoxia Is Associated With Macrophage Inflammatory Profiles as Revealed by Cellular Genome-Wide Association.Semantic proximity Read ↗

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages.Semantic proximity Read ↗

Nitric oxide brings innate immune resistance to M. tuberculosis infection among high-risk household contacts of pulmonary tuberculosis patients.Semantic proximity Read ↗

Molecular Mechanisms of Increased Nitric Oxide (NO) in Asthma: Evidence for Transcriptional and Post-Translational Regulation of NO SynthesisSemantic proximity Read ↗

Identification of Macrophage Arginase I as a New Candidate Gene of Atherosclerosis ResistanceSemantic proximity Read ↗

Nitric oxide synthase and its function in animal reproduction: an updateSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.