Article
Capicua (CIC) mutations in gliomas in association with MAPK activation for exposing a potential therapeutic target.
Medical oncology (Northwood, London, England) - 8 Jun 2023
Darabi Sourat, Xiu Joanne, Samec Timothy, Kesari Santosh, Carrillo Jose, Aulakh Sonikpreet, Walsh Kyle M, Sengupta Soma, Sumrall Ashley, Spetzler David, Glantz Michael, Demeure Michael J
Abstract excerpt
Gliomas are the most prevalent neurological cancer in the USA and care modalities are not able to effectively combat these aggressive malignancies. Identifying new, more effective treatments require a deep understanding of the complex genetic variations and relevant pathway associations behind these cancers. Drawing connections between gene mutations with a responsive genetic target can help drive therapy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.