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Diabetes ExacerbatesPseudomonas aeruginosaKeratitis in Streptozotocin-Induced and db/db Mice via Altering Programmed Cell Death Pathways

6 Jun 2023

Abstract excerpt

Purpose: Patients with diabetes have a higher incidence of infections, which are often more severe. This study aimed to investigate the impact of hyperglycemia on bacterial keratitis caused by Pseudomonas aeruginosa (Pa) in two mouse models of diabetes, streptozotocin-induced type 1 diabetes mellitus (T1DM) and db/db type 2 diabetes mellitus. Methods: The susceptibility of corneas to Pa was assessed by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37279395
DOI: 10.1167/iovs.64.7.14

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