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Article

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response

13 Jun 2008

Abstract excerpt

BACKGROUND: Despite advances in the understanding of diabetic retinopathy, the nature and time course of molecular changes in the retina with diabetes are incompletely described. This study characterized the functional and molecular phenotype of the retina with increasing durations of diabetes. RESULTS: Using the streptozotocin-induced rat model of diabetes, levels of retinal permeability, caspase activity, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18554398
DOI: 10.1186/1755-8794-1-26

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