Article
Group-specific cellular metabolism in Medulloblastoma.
Journal of translational medicine - 5 Jun 2023
Funke Viktoria L E, Walter Carolin, Melcher Viktoria, Wei Lanying, Sandmann Sarah, Hotfilder Marc, Varghese Julian, Jäger Natalie, Kool Marcel, Jones David T W, Pfister Stefan M, Milde Till, Mynarek Martin, Rutkowski Stefan, Seggewiss Jochen, Jeising Daniela, de Faria Flavia W, Marquardt Thorsten, Albert Thomas K, Schüller Ulrich, Kerl Kornelius
Abstract excerpt
BACKGROUND: Cancer metabolism influences multiple aspects of tumorigenesis and causes diversity across malignancies. Although comprehensive research has extended our knowledge of molecular subgroups in medulloblastoma (MB), discrete analysis of metabolic heterogeneity is currently lacking. This study seeks to improve our understanding of metabolic phenotypes in MB and their impact on patients' outcomes. METHODS:...
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