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Article

The metabolomic signature of malignant glioma reflects accelerated anabolic metabolism.

Cancer research - 15 Nov 2012

Chinnaiyan Prakash, Kensicki Elizabeth, Bloom Gregory, Prabhu Antony, Sarcar Bhaswati, Kahali Soumen, Eschrich Steven, Qu Xiaotao, Forsyth Peter, Gillies Robert

Abstract excerpt

Although considerable progress has been made toward understanding glioblastoma biology through large-scale genetic and protein expression analyses, little is known about the underlying metabolic alterations promoting their aggressive phenotype. We conducted global metabolomic profiling on patient-derived glioma specimens and identified specific metabolic programs differentiating low- and high-grade tumors, with...

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Source

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Identifiers

PMID: 23026133
DOI: 10.1158/0008-5472.CAN-12-1572-T
PMCID: PMC4638418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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