Article
Molecular and cellular heterogeneity: the hallmark of glioblastoma.
Neurosurgical focus - 1 Dec 2014
Aum Diane J, Kim David H, Beaumont Thomas L, Leuthardt Eric C, Dunn Gavin P, Kim Albert H
Abstract excerpt
There has been increasing awareness that glioblastoma, which may seem histopathologically similar across many tumors, actually represents a group of molecularly distinct tumors. Emerging evidence suggests that cells even within the same tumor exhibit wide-ranging molecular diversity. Parallel to the discoveries of molecular heterogeneity among tumors and their individual cells, intense investigation of the...
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