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Article

Interplay among replicative and specialized DNA polymerases determines failure or success of translesion synthesis pathways.

Journal of molecular biology - 28 Sept 2007

Fujii Shingo, Fuchs Robert P

Abstract excerpt

Living cells possess a panel of specialized DNA polymerases that deal with the large diversity of DNA lesions that occur in their genomes. How specialized DNA polymerases gain access to the replication intermediate in the vicinity of the lesion is unknown. Using a model system in which a single replication blocking lesion can be bypassed concurrently by two pathways that leave distinct molecular signatures, we...

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Identifiers

PMID: 17707403
DOI: 10.1016/j.jmb.2007.07.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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